Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31464225 | 0.85 | ALOX15 (0.48) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL1320631 | 0.85 | ALOX15 (0.48) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL11782386 | 0.74 | TSHR (0.50) | CYP1A2MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL17028590 | 0.74 | ENPP2 (0.58) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL8426740 | 0.72 | ENPP2 (0.56) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL6341765 | 0.72 | ENPP2 (0.61) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL3150055 | 0.72 | ENPP2 (0.56) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL29713840 | 0.72 | ENPP2 (0.56) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL6382767 | 0.72 | ENPP2 (0.50) | ENPP2DRD2DRD1TAAR1ALOX15 | |
| SCHEMBL7359415 | 0.72 | ENPP2 (0.50) | ENPP2DRD2DRD1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208108-A1 | COMPOUND FOR REDUCING URIC ACID | 江苏新元素医药科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116715633-A | Compounds useful for uric acid reduction | 江苏新元素医药科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-7763600-B2 | Hormone-based nitrogen monoxide donor compounds and use thereof in obstetrics and gynecology | EFFIK (FR) | 2010-07-27 | — | — | US | disclosed |
| US-20050222105-A1 | Hormone-based nitrogen monoxide donor compounds and use thereof in obstetrics and gynecology | EFFIK (FR) | 2005-10-06 | — | — | US | disclosed |
| WO-2004041803-A1 | NITRIC OXIDE RELEASING PRODRUGS OF DIARYL-2-(5H)-FURANONES AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222105-A1 | Hormone-based nitrogen monoxide donor compounds and use thereof in obstetrics and gynecology | PGF, SHBG, GNRHR | ENPP2 3814/4885DRD2 537/4885DRD1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.