Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | TRHR | P34981 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925778 | 0.96 | ACE (0.43) | ACEOPRK1TRHRMEN1KMT2A | |
| SCHEMBL29590547 | 0.90 | OPRK1 (0.46) | ACEOPRK1TRHRMEN1KMT2A | |
| SCHEMBL29630560 | 0.90 | OPRK1 (0.46) | ACEOPRK1TRHRMEN1KMT2A | |
| SCHEMBL29630369 | 0.90 | TRHR (0.41) | ACETRHRF2RACE2 | |
| SCHEMBL30258236 | 0.89 | F2 (0.45) | OPRK1APLNRF2RF2MC4R | |
| SCHEMBL30454445 | 0.88 | CAPN1 (0.46) | ACEOPRK1APLNRCAPN1F2 | |
| SCHEMBL29630670 | 0.88 | TRHR (0.42) | ACEOPRK1TRHRACE2 | |
| SCHEMBL29555153 | 0.87 | F2 (0.46) | APLNRF2REN | |
| SCHEMBL29630596 | 0.87 | MEN1 (0.43) | ACEOPRK1TRHRMEN1KMT2A | |
| SCHEMBL29630457 | 0.86 | MC4R (0.42) | TRHRF2MC4RREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789180-B | KIF 13B-derived peptides and methods of inhibiting angiogenesis | 伊利诺伊大学理事会 | 2023-09-08 | — | — | CN | disclosed |
| US-11299524-B2 | KIF13B-derived peptide and method of inhibiting angiogenesis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-12 | — | — | US | disclosed |