SCHEMBL30454445

SCHEMBL30454445

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nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 5/20 0.46
▸ SLC6A2 P23975 1/20 0.45
▸ CTSB P07858 3/20 0.43
▸ OPRK1 P41145 5/20 0.42
▸ APLNR P35414 1/20 0.41
▸ F2 P00734 4/20 0.40
▸ PLK1 P53350 1/20 0.40
▸ REN P00797 1/20 0.39
▸ ACE P12821 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30498899 0.91 SLC6A2 (0.42) CAPN1SLC6A2CTSBOPRK1REN
SCHEMBL30611006 0.90 CAPN1 (0.44) CAPN1SLC6A2CTSBOPRK1APLNR
SCHEMBL5533523 0.89 SLC6A2 (0.43) CAPN1SLC6A2CTSBOPRK1APLNR
SCHEMBL28081211 0.89 SLC6A2 (0.43) CAPN1SLC6A2CTSBOPRK1APLNR
SCHEMBL5533513 0.89 SLC6A2 (0.43) CAPN1SLC6A2CTSBOPRK1APLNR
SCHEMBL29608052 0.89 SLC6A2 (0.47) CAPN1SLC6A2CTSBF2REN
SCHEMBL29555036 0.88 ACE (0.41) CAPN1OPRK1APLNRF2REN
SCHEMBL29590547 0.88 OPRK1 (0.46) SLC6A2OPRK1RENACE
SCHEMBL29630560 0.88 OPRK1 (0.46) SLC6A2OPRK1RENACE
SCHEMBL29608127 0.88 REN (0.49) CAPN1SLC6A2F2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO claimed
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (OR) 2024-10-17 — — US disclosed
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA ARGLU1, TPX2, RXFP1 CAPN1 2929/4885SLC6A2 1923/4885CTSB 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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