Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556598 | 0.90 | TP53 (0.70) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556240 | 0.89 | TP53 (0.55) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556242 | 0.89 | MAPT (0.60) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556193 | 0.89 | MAPT (0.60) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556244 | 0.89 | TP53 (0.55) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556232 | 0.88 | RAB9A (0.52) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL29556941 | 0.84 | GAA (0.59) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL19707566 | 0.82 | GAA (0.65) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL29556965 | 0.82 | MAPT (0.52) | TP53TSHRRAB9AHTTALDH1A1 | |
| SCHEMBL4893387 | 0.81 | TP53 (0.87) | TP53TSHRRAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |