Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 12/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 10/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556591 | 0.90 | TP53 (0.60) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL31040569 | 0.89 | TP53 (0.87) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL4893387 | 0.89 | TP53 (0.87) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL17084260 | 0.87 | TP53 (0.84) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL29556232 | 0.85 | RAB9A (0.52) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL4345400 | 0.85 | RAB9A (0.69) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL29556193 | 0.85 | MAPT (0.60) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL29556242 | 0.85 | MAPT (0.60) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL14442613 | 0.84 | TP53 (0.84) | TP53TSHRRAB9AALDH1A1HTT | |
| SCHEMBL7610775 | 0.84 | TP53 (0.73) | TP53TSHRRAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |