Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948793 | 1.00 | OPRM1 (0.37) | OPRM1MAPTLMNARAB9AKDM4E | |
| SCHEMBL1951446 | 0.84 | GRIN2B (0.37) | OPRM1MAPTLMNARAB9AKDM4E | |
| SCHEMBL28172775 | 0.83 | OPRD1 (0.35) | OPRM1MAPTLMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL26650155 | 0.78 | KDM1A (0.47) | — | |
| SCHEMBL11297637 | 0.77 | KDM1A (0.54) | OPRM1OPRK1 | |
| SCHEMBL12005732 | 0.77 | MAPT (0.33) | OPRM1MAPTLMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11296787 | 0.75 | KDM1A (0.52) | OPRM1ALDH1A1OPRK1 | |
| Hydrochloric Acid SCHEMBL27925454 | 0.74 | OPRD1 (0.35) | OPRM1MAPTLMNARAB9AKDM4E | |
| SCHEMBL1950165 | 0.74 | OPRM1 (0.44) | OPRM1MAPTKDM4EOPRD1OPRK1 | |
| SCHEMBL28292428 | 0.74 | PNMT (0.50) | MAPTLMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315796-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-04-12 | — | — | CN | disclosed |