Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.42 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11296787 | 0.98 | KDM1A (0.52) | KDM1ADRD2DRD3CA2KYAT1 | |
| SCHEMBL11290168 | 0.88 | DRD2 (0.50) | KDM1ADRD2DRD3KYAT1KYAT3 | |
| Hydrochloric Acid SCHEMBL11291604 | 0.86 | DRD2 (0.49) | KDM1ADRD2DRD3KYAT1KYAT3 | |
| SCHEMBL3951310 | 0.85 | KDM1A (0.57) | KDM1ADRD2DRD3CA2ACHE | |
| SCHEMBL8768777 | 0.77 | DRD2 (0.54) | KDM1ADRD2DRD3ADRB2HTR1A | |
| SCHEMBL8767448 | 0.77 | DRD2 (0.54) | KDM1ADRD2DRD3ADRB2HTR1A | |
| SCHEMBL29557992 | 0.77 | OPRM1 (0.37) | OPRM1OPRK1 | |
| SCHEMBL1948793 | 0.77 | OPRM1 (0.37) | OPRM1OPRK1 | |
| SCHEMBL29119570 | 0.76 | DRD2 (0.47) | KDM1ADRD2DRD3CA2KYAT1 | |
| SCHEMBL11290721 | 0.75 | CYP3A4 (0.43) | CA2MAOAACHEOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005821-B1 | INDANAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-12-08 | — | — | EP | disclosed |