SCHEMBL29559031

SCHEMBL29559031

O=C(O)c1ccc2c(c1)CCC(C(=O)O)C2

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 2/20 0.43
SRD5A2 P31213 4/20 0.42
SRD5A1 P18405 3/20 0.42
DRD3 P35462 1/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 1/20 0.42
BLM P54132 1/20 0.42
GRM1 Q13255 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
AKR1C3 P42330 1/20 0.42
KDM1A O60341 2/20 0.41
FAAH O00519 2/20 0.40
MCHR1 Q99705 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232699 1.00 ALDH1A1 (0.56) ALDH1A1TDP1SRD5A2SRD5A1DRD3
SCHEMBL8370381 0.93 ALDH1A1 (0.56) ALDH1A1TDP1SRD5A2SRD5A1KDM4E
SCHEMBL7275357 0.87 ALDH1A1 (0.53) ALDH1A1TDP1SRD5A2SRD5A1DRD3
SCHEMBL1107094 0.87 NPC1 (0.49) ALDH1A1DRD3MAPTPOLBFAAH
SCHEMBL19718187 0.86 ALDH1A1 (0.53) ALDH1A1TDP1SRD5A2SRD5A1KDM4E
SCHEMBL10721805 0.83 ALDH1A1 (0.49) ALDH1A1TDP1DRD3KMT2AFAAH
SCHEMBL8880658 0.83 FAAH (0.47) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL346833 0.81 OPRK1 (0.57) DRD3FAAH
SCHEMBL16252317 0.81 OPRK1 (0.57) DRD3FAAH
SCHEMBL8537094 0.81 ALDH1A1 (0.58) ALDH1A1TDP1SRD5A2SRD5A1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843471-A Method for purifying 2, 6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2024-04-09 CN claimed
CN-119219484-A Preparation method of PET-PEN copolyester monomer 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-117843471-A Method for purifying 2, 6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2024-04-09 CN disclosed
CN-114426480-B Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-114426480-B Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-112521271-B Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-08-04 CN disclosed
CN-112521272-B Hydrogenation purification method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-04-07 CN disclosed
CN-114426480-A Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2022-05-03 CN disclosed
CN-114426480-A Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2022-05-03 CN disclosed