Phyllostin

Phyllostin

SCHEMBL29559142

COC(=O)C1=C[C@@H](O)[C@@H]2OC(=O)[C@@H](C)O[C@H]2C1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14259702 0.83 CHRM3 (0.33) LMNA
SCHEMBL15929795 0.74 SLC6A3 (0.33) LMNA
SCHEMBL26989699 0.71 MMP1 (0.35)
SCHEMBL21703854 0.71 MMP1 (0.35)
(-)-Methyl Shikimate SCHEMBL15983807 0.67 ALDH1A1 (0.36) LMNA
SCHEMBL29999265 0.67
SCHEMBL8588994 0.66
SCHEMBL14905976 0.66 CHRM3 (0.36) LMNA
SCHEMBL1716907 0.66 CHRM3 (0.36) LMNA
SCHEMBL3006812 0.66 CHRM3 (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115094449-B Method for synthesizing and marking halogenated indolone by using freon-type methane as carbon-synthesis son and application thereof 上海交通大学 2024-02-23 CN claimed
CN-115094449-A Method for synthesizing and marking halogenated indolone by using freon type methane as carbon-carbon synthesizer and application thereof 上海交通大学 2022-09-23 CN claimed
CN-115286634-A Synthetic method of thiocyano tetrahydropyrrolo indoline compound 常州工程职业技术学院 2022-11-04 CN disclosed
CN-115094449-A Method for synthesizing and marking halogenated indolone by using freon type methane as carbon-carbon synthesizer and application thereof 上海交通大学 2022-09-23 CN disclosed
CN-113632679-B Disease-preventing cultivation method for kiwi fruits 重庆文理学院 2022-04-12 CN disclosed