Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866574 | 1.00 | HPGDS (0.31) | HPGDS | |
| SCHEMBL22866471 | 0.83 | L3MBTL1 (0.34) | HPGDS | |
| SCHEMBL28713249 | 0.81 | PIM1 (0.39) | — | |
| SCHEMBL29661801 | 0.80 | UGT8 (0.31) | HPGDS | |
| SCHEMBL22866572 | 0.80 | UGT8 (0.31) | HPGDS | |
| SCHEMBL29661871 | 0.80 | UGT8 (0.31) | HPGDS | |
| SCHEMBL22866552 | 0.80 | UGT8 (0.31) | HPGDS | |
| SCHEMBL22866573 | 0.79 | UGT8 (0.33) | HPGDS | |
| SCHEMBL22866554 | 0.78 | PTPRB (0.33) | — | |
| SCHEMBL29561004 | 0.78 | PTPRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994139-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | Effector Therapeutics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114269756-A | 4-oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds inhibiting EIF4E | 效应疗法股份有限公司 | 2022-04-01 | — | — | CN | disclosed |