Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815799 | 0.96 | OPRM1 (0.49) | PRCPF2PRSS1OPRM1OPRK1 | |
| SCHEMBL30540072 | 0.91 | OPRM1 (0.50) | F2OPRM1OPRK1EPHA2NMUR2 | |
| SCHEMBL31437210 | 0.91 | ACE (0.44) | PRCPF2PRSS1OPRM1OPRK1 | |
| SCHEMBL29561678 | 0.88 | CTRB1 (0.42) | PRCPF2OPRM1OPRK1 | |
| SCHEMBL29812564 | 0.88 | PRCP (0.43) | PRCPOPRM1OPRK1 | |
| SCHEMBL31437193 | 0.87 | PRCP (0.51) | PRCP | |
| SCHEMBL31467758 | 0.87 | PRCP (0.46) | PRCPOPRM1OPRK1EPHA2 | |
| SCHEMBL31467771 | 0.85 | PRCP (0.43) | PRCPF2OPRM1OPRK1EPHA2 | |
| SCHEMBL29693015 | 0.85 | OPRM1 (0.53) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL29872221 | 0.85 | DPP4 (0.52) | OPRM1OPRK1EPHA2NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204611-B | Solid phase fragment method for synthesizing bivalirudin | 海南中和药业股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-110204611-B | Solid phase fragment method for synthesizing bivalirudin | 海南中和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-11643439-B2 | Multi-target compound with anticoagulation and antiplatelet activity, preparation method therefor, and use thereof | SHAANXI MICOT TECHNOLOGY LIMITED COMPANY (CN) | 2023-05-09 | — | — | US | disclosed |
| CN-107406480-B | Peptide synthesis method | JITSUBO株式会社 | 2022-06-24 | — | — | CN | disclosed |
| CN-112062835-B | Preparation method of bivalirudin | 扬子江药业集团四川海蓉药业有限公司 | 2022-04-26 | — | — | CN | disclosed |