Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | UQCRB | P14927 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275069 | 0.91 | ACLY (0.69) | ACLYGAAMEN1KMT2AMAPT | |
| SCHEMBL29561469 | 0.86 | PKM (0.64) | MEN1KMT2APGRCES1CYP3A4 | |
| SCHEMBL3260803 | 0.84 | GAA (0.71) | GAAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29562342 | 0.84 | PGR (0.72) | GAAMEN1KMT2APGRCES1 | |
| SCHEMBL29561466 | 0.83 | PGR (0.57) | MEN1KMT2APGRCES1CYP3A4 | |
| SCHEMBL29561400 | 0.83 | ALDH1A1 (0.71) | MEN1KMT2AMAPK1PGRCES1 | |
| SCHEMBL29561505 | 0.83 | PGR (0.57) | ACLYMEN1KMT2APGRCES1 | |
| SCHEMBL28279840 | 0.83 | ACLY (0.64) | ACLYMEN1KMT2APGR | |
| SCHEMBL29561444 | 0.80 | CES1 (0.81) | ACLYGAAMAPTHTTPGR | |
| SCHEMBL29561264 | 0.80 | ACLY (0.62) | ACLYGAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |