Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL2956203

F[n+]1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
KCNH2 Q12809 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8231526-A None JP disclosed
US-9701684-B2 Chiral fluorinating reagents OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2017-07-11 US disclosed
US-20150284401-A1 CHIRAL FLUORINATING REAGENTS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2015-10-08 US disclosed
EP-2914582-A2 CHIRAL FLUORINATING REAGENTS Isis Innovation Limited (GB) 2015-09-09 EP disclosed
WO-2014068341-A2 CHIRAL FLUORINATING REAGENTS ISIS INNOVATION LIMITED (GB) 2014-05-08 WO disclosed
US-7754885-B2 Tubulysins, method for producing the same and tubulysin preparations HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) 2010-07-13 US disclosed
US-20060128754-A1 Tubulysins, method for producing the same and tubulysin preparations HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) 2006-06-15 US disclosed
EP-1201627-B1 Ring fluorination of non-activated aromatic compounds AIR PROD & CHEM (US) 2005-12-14 EP disclosed
EP-1201628-B1 Electrophilic fluorination AIR PROD & CHEM (US) 2005-12-14 EP disclosed
US-6737525-B2 USEFUL IN FLUORINATING, PREFERABLY IN A NITROMETHANE SOLVENT, CARBANIONIC SPECIES AND/OR ACTIVATED AROMATIC COMPOUNDS AIR PRODUCTS AND CHEMICALS, INC. 2004-05-18 US disclosed
EP-1100785-A1 SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES Aventis CropScience GmbH (DE) 2001-05-23 EP disclosed
US-6197729-B1 COMBATING PEST WHICH COMPRISES APPLYING TO PEST OR ITS LOCUS PESTICIDAL CYCLOHEXYLAMINOPYRIMIDINNE COMPOUND HOECHST SCHERING AGREVO (DE) 2001-03-06 US disclosed
WO-2000007998-A1 SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-17 WO disclosed
EP-0741730-B1 1-SUBSTITUTED-4-FLUORO-1,4-DIAZONIABICYCLO 2.2.2]OCTANE SALTS AND THEIR APPLICATION AS FLUORINATING AGENTS ALLIED SIGNAL INC (US) 1999-10-06 EP disclosed
EP-0646979-B1 MATERIAL FOR GENERATING ELECTRIC ENERGY DAIKIN IND LTD (JP) 1998-11-11 EP disclosed
US-5606084-A Process of fluorinating organic compounds with 1-substituted-4-fluoro-1,4-diazoniabicyclo octane salts ALLIEDSIGNAL INC. (US) 1997-02-25 US disclosed
US-5573868-A ELECTROCHEMICAL REACTION BETWEEN A COMPOUND HAVING A N-F BOND AND ELECTRON DONOR DAIKIN INDUSTRIES, LTD. (JP) 1996-11-12 US disclosed
JP-H08231526-A FLUOROLACTONE AND ITS PRODUCTION CHICHIBU ONODA CEMENT CORP 1996-09-10 JP disclosed
US-5459267-A 1-substituted-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane salts and their application as fluorinating agents ALLIEDSIGNAL INC. (US) 1995-10-17 US disclosed
EP-0646979-A1 MATERIAL FOR GENERATING ELECTRIC ENERGY DAIKIN INDUSTRIES, LTD. (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284401-A1 CHIRAL FLUORINATING REAGENTS TIAM1, AFF2, AFF1 GPR3 1333/4885KCNH2 1644/4885ACHE 3151/4885
US-20060128754-A1 Tubulysins, method for producing the same and tubulysin preparations ATP6V1B1, OR10J3, NR1H3 GPR3 292/4885KCNH2 502/4885ACHE 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.