Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562105 | 0.91 | MAPT (0.61) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29562114 | 0.85 | MAPT (0.66) | ALDH1A1MAPTPTGDR2LMNAPKM | |
| SCHEMBL29561797 | 0.84 | MAPT (0.61) | ALDH1A1MAPTLMNAPKMPGR | |
| SCHEMBL29561514 | 0.82 | MAPT (0.65) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29561330 | 0.81 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29562337 | 0.81 | MAPT (0.58) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL29562119 | 0.81 | MAPT (0.64) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL29561463 | 0.81 | MAPT (0.67) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29561313 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2ALMNAPKM | |
| SCHEMBL29561129 | 0.80 | MAPT (0.65) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |