Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.42 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.42 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562119 | 0.85 | MAPT (0.64) | MAPTPKMPGRNPSR1CCR2 | |
| SCHEMBL29561797 | 0.81 | MAPT (0.61) | MAPTPKMPGRPTGES2TP53 | |
| SCHEMBL29562498 | 0.81 | ALDH1A1 (0.62) | MAPTPKMPGRLMNAMEN1 | |
| SCHEMBL29562105 | 0.81 | MAPT (0.61) | MAPTPKMPGRCCR2GPR27 | |
| SCHEMBL29562114 | 0.80 | MAPT (0.66) | MAPTPKMPGRTP53LMNA | |
| SCHEMBL29561514 | 0.80 | MAPT (0.65) | MAPTPKMPGRTP53LMNA | |
| SCHEMBL29561330 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2A | |
| SCHEMBL29562337 | 0.78 | MAPT (0.58) | MAPTPKMPTGES2TP53LMNA | |
| SCHEMBL29561463 | 0.78 | MAPT (0.67) | MAPTPKMPGRTP53LMNA | |
| SCHEMBL29561129 | 0.77 | MAPT (0.65) | MAPTPKMPGRTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |