Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760631 | 0.81 | MEN1 (0.47) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL2724212 | 0.79 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL8895118 | 0.76 | S100A4 (0.47) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL25835259 | 0.76 | POLB (0.51) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL12822665 | 0.76 | POLB (0.51) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL25835313 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL29244104 | 0.71 | KMT2A (0.46) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL28680129 | 0.71 | POLB (0.54) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL21646073 | 0.69 | HTT (0.49) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 | |
| SCHEMBL28357232 | 0.68 | MAPT (0.44) | ALDH1A1L3MBTL1RECQLALOX12EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231146-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF GLAUCOMA | Mazence Inc. (KR) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009082124-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF GLAUCOMA | MAZENCE INC. (KR) | 2009-07-02 | — | — | WO | disclosed |