Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18260522 | 1.00 | KDM4E (0.39) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27141821 | 0.82 | ATR (0.42) | MEN1KMT2A | |
| SCHEMBL29565827 | 0.79 | KDM4E (0.38) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL16856891 | 0.79 | KDM4E (0.38) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18383188 | 0.76 | ALDH1A1 (0.43) | KDM4EMEN1KMT2ARAB9AMITF | |
| SCHEMBL2587336 | 0.73 | S1PR2 (0.62) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL31748884 | 0.72 | RAB9A (0.43) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL25137117 | 0.71 | ATR (0.40) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL25136736 | 0.71 | ATR (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8365771 | 0.70 | L3MBTL1 (0.42) | KDM4ERAB9AALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111362975-B | Naphthyridine compounds as JAK kinase inhibitors | 施万生物制药研发IP有限责任公司 | 2022-04-05 | — | — | CN | disclosed |