Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532256 | 0.79 | L3MBTL1 (0.42) | L3MBTL1CETPGAAKDM4EHTT | |
| SCHEMBL29590212 | 0.72 | CETP (0.49) | L3MBTL1CETPGAAKDM4EHTT | |
| SCHEMBL14716225 | 0.72 | CETP (0.49) | L3MBTL1CETPGAAKDM4EHTT | |
| SCHEMBL15667865 | 0.70 | PDK1 (0.47) | L3MBTL1CETPGAAKDM4EHTT | |
| SCHEMBL18260522 | 0.70 | KDM4E (0.39) | L3MBTL1CETPKDM4EHTTALDH1A1 | |
| SCHEMBL29565434 | 0.70 | KDM4E (0.39) | L3MBTL1CETPKDM4EHTTALDH1A1 | |
| SCHEMBL31748884 | 0.70 | RAB9A (0.43) | L3MBTL1CETPKDM4EHTTALDH1A1 | |
| SCHEMBL16503536 | 0.70 | L3MBTL1 (0.48) | L3MBTL1CETPGAAHTTNPSR1 | |
| SCHEMBL5515821 | 0.70 | IDO1 (0.34) | — | |
| SCHEMBL23879399 | 0.69 | HDAC1 (0.48) | L3MBTL1CETPKDM4EHTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638566-B1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO KK (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5539112-A | 5-aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0638566-A1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |