Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534265 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAEGFRGFERPOLB | |
| SCHEMBL950218 | 0.80 | LMNA (0.73) | SMN1; SMN2LMNAEGFRGFERPOLB | |
| SCHEMBL9876387 | 0.78 | PARP1 (0.55) | SMN1; SMN2LMNAEGFRKDM4EMAPT | |
| SCHEMBL5536914 | 0.77 | L3MBTL1 (0.46) | SMN1; SMN2LMNAPOLBL3MBTL1CYP1A2 | |
| SCHEMBL9206405 | 0.77 | KDM4E (0.61) | SMN1; SMN2LMNAL3MBTL1KDM4EMAPT | |
| SCHEMBL5539360 | 0.76 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAEGFRGFERPOLB | |
| SCHEMBL3709112 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAEGFRGFERPOLB | |
| SCHEMBL9772541 | 0.76 | KMT2A (0.54) | SMN1; SMN2LMNAPOLBL3MBTL1CYP1A2 | |
| SCHEMBL14570482 | 0.76 | RAB9A (0.43) | SMN1; SMN2LMNAPOLBL3MBTL1CYP1A2 | |
| SCHEMBL2162312 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAEGFRGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869369-B | Five-membered and six-membered nitrogen heteroaromatic ring compound, preparation method thereof, medicinal composition and application thereof | 厦门大学 | 2022-06-28 | — | — | CN | disclosed |
| US-11292787-B2 | Five-membered-fused-six-membered aza-aromatic ring compound, preparation method thereof, pharmaceutical composition and application thereof | XIAMEN UNIVERSITY (CN) | 2022-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292787-B2 | Five-membered-fused-six-membered aza-aromatic ring compound, preparation method thereof, pharmaceutical composition and application thereof | KRAS, NRAS, RASSF5 | SMN1; SMN2 4144/4885LMNA 4198/4885EGFR 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.