SCHEMBL29565883

SCHEMBL29565883

NC(=O)c1nc2ccc3cccnc3c2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.50
MAPT P10636 8/20 0.43
LMNA P02545 5/20 0.43
TP53 P04637 5/20 0.43
KDM4E B2RXH2 2/20 0.43
GMNN O75496 1/20 0.43
HSP90AA1 P07900 1/20 0.43
MMP2 P08253 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MMP9 P14780 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
MMP8 P22894 1/20 0.43
CCR1 P32246 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
MMP13 P45452 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28407139 0.87 TET2 (0.49) PARP1MAPTLMNATP53KDM4E
Ammonia Solution, Strong SCHEMBL28923724 0.85 TET2 (0.48) PARP1MAPTLMNATP53KDM4E
Ammonia Solution, Strong SCHEMBL30628009 0.85 TET2 (0.48) PARP1MAPTLMNATP53KDM4E
SCHEMBL28399094 0.84 MAPT (0.42) PARP1MAPTLMNATP53KDM4E
SCHEMBL11403564 0.83 HDAC6 (0.46) MAPTLMNATP53KDM4EGMNN
SCHEMBL10477389 0.82 ALOX15 (0.48) MAPTLMNATP53KDM4EALOX15
SCHEMBL26918441 0.77 MAPT (0.47) MAPTLMNATP53KDM4EGMNN
SCHEMBL88110 0.76 LMNA (0.50) MAPTLMNATP53KDM4EGMNN
SCHEMBL29740308 0.76 LMNA (0.50) MAPTLMNATP53KDM4EGMNN
SCHEMBL9803452 0.76 MAPT (0.46) PARP1MAPTLMNATP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220176094-A1 NEEDLING DEVICE AND DRUG APPLICATOR FOLLICA INC (US) 2022-06-09 US disclosed
EP-3981337-A1 NEEDLING DEVICE Follica, Inc. (US) 2022-04-13 EP disclosed