SCHEMBL88110

SCHEMBL88110

Nc1nc2ccc3cccnc3c2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
TSHR P16473 3/20 0.50
TP53 P04637 3/20 0.50
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
HSP90AA1 P07900 2/20 0.50
HTT P42858 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MMP2 P08253 2/20 0.50
CYP3A4 P08684 2/20 0.50
GMNN O75496 1/20 0.50
CYP2D6 P10635 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
MMP8 P22894 1/20 0.50
THPO P40225 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740308 1.00 LMNA (0.50) LMNAMAPTKDM4ETSHRTP53
SCHEMBL29740307 0.98 LMNA (0.48) LMNAMAPTKDM4ETSHRTP53
SCHEMBL7325665 0.80 ALDH1A1 (0.44) MAPTKDM4ETDP1NUDT1TYMS
SCHEMBL31064745 0.79 MAPT (0.55) LMNAMAPTKDM4ETSHRTP53
SCHEMBL9803225 0.79 MAPT (0.55) LMNAMAPTKDM4ETSHRTP53
SCHEMBL8544920 0.79 LMNA (0.50) LMNAMAPTKDM4ETSHRTP53
SCHEMBL9803452 0.79 MAPT (0.46) LMNAMAPTKDM4ETSHRTP53
SCHEMBL1490778 0.78 NUDT1 (0.42) LMNAMAPTKDM4ETSHRTP53
SCHEMBL10656134 0.78 MAPT (0.48) LMNAMAPTKDM4ETSHRTP53
SCHEMBL3822260 0.76 CA1 (0.50) LMNAMAPTKDM4ETSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 US claimed
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 US claimed
EP-4648801-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 EP claimed
EP-4648800-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 EP claimed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 EP claimed
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-04-10 US claimed
WO-2024151890-A9 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-08-22 WO claimed
WO-2024151890-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
WO-2024149345-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
EP-4366777-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-15 EP claimed
WO-2003094836-A2 METHODS AND PRODUCTS FOR ENHANCING IMMUNE RESPONSES USING IMIDAZOQUINOLINE COMPOUNDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2003-11-20 WO claimed
US-20030190308-A1 Adjuvant BRAUN RALPH P (US) 2003-10-09 US claimed
US-20030185835-A1 Adjuvant for vaccines POWDERJECT RESEARCH LIMITED (GB) 2003-10-02 US claimed
WO-2003080114-A2 IMIDAZOQUINOLINE ADJUVANTS FOR VACCINES POWDERMED LIMITED (GB) 2003-10-02 WO claimed
WO-2003080112-A2 IMIDAZOQUINOLINEAMINES AS ADJUVANTS IN HIV DNA VACCINATION POWDERMED LIMITED (GB) 2003-10-02 WO claimed
WO-2003072026-A2 METHOD OF REDUCING AND TREATING UVB-INDUCED IMMUNOSUPPRESSION 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-09-04 WO claimed
US-20030161797-A1 Method of reducing and treating UVB-induced immunosuppression 3M INNOVATIVE PROPERTIES COMPANY 2003-08-28 US claimed
US-20030139364-A1 Methods and products for enhancing immune responses using imidazoquinoline compounds UNIVERSITY OF IOWA RESEARCH FOUNDATION 2003-07-24 US claimed
WO-2003043572-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR PATHWAYS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-05-30 WO claimed
US-6486168-B1 Formulations and methods for treatment of mucosal associated conditions with an immune response modifier 3M INNOVATIVE PROPERTIES COMPANY 2002-11-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME CSGALNACT1, SLC43A1, OSTC LMNA 1233/4885MAPT 2416/4885KDM4E 3970/4885
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME PTK2B, PTK2, LTK LMNA 4448/4885MAPT 3765/4885KDM4E 2816/4885
US-20030190308-A1 Adjuvant TLR9, TLR3, TLR5 LMNA 3172/4885MAPT 2002/4885KDM4E 4173/4885
US-20030185835-A1 Adjuvant for vaccines TLR9, TLR3, TLR5 LMNA 2386/4885MAPT 3170/4885KDM4E 4456/4885
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME MGAT3, GALE, GPI LMNA 775/4885MAPT 1457/4885KDM4E 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.