Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565850 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3362215 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL29565914 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL11457192 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL1269496 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL29567047 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL6045246 | 0.80 | TDP1 (0.48) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL11474747 | 0.80 | TDP1 (0.48) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL11983774 | 0.77 | CA12 (0.50) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL10315741 | 0.77 | CA12 (0.50) | KDM4EALDH1A1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378209-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2025-08-05 | — | — | US | disclosed |
| US-20220332690-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2022-10-20 | — | — | US | disclosed |
| US-11312693-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312693-B2 | Protease inhibitors | CTSK, CTSF, CTSS | KDM4E 3773/4885ALDH1A1 3140/4885HPGD 3002/4885 |
| US-12378209-B2 | Protease inhibitors | MMP26, CTSK, TMPRSS6 | KDM4E 3767/4885ALDH1A1 2959/4885HPGD 3029/4885 |
| US-20220332690-A1 | PROTEASE INHIBITORS | MMP26, CTSK, TMPRSS6 | KDM4E 3767/4885ALDH1A1 2959/4885HPGD 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.