Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BAZ1A | Q9NRL2 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507524 | 1.00 | PRMT3 (0.45) | PRMT3ALDH1A1NPC1POLBMAPT | |
| SCHEMBL3205606 | 0.85 | HSD17B10 (0.50) | ALDH1A1NPC1POLBMAPTRAB9A | |
| SCHEMBL764255 | 0.81 | NPC1 (0.50) | PRMT3ALDH1A1NPC1POLBMAPT | |
| SCHEMBL7576448 | 0.74 | MAPT (0.46) | ALDH1A1NPC1POLBMAPTRAB9A | |
| SCHEMBL16782399 | 0.71 | ALDH1A1 (0.44) | PRMT3ALDH1A1NPC1POLBMAPT | |
| SCHEMBL1292012 | 0.69 | SMN1; SMN2 (0.46) | ALDH1A1NPC1POLBMAPTRAB9A | |
| SCHEMBL17538782 | 0.69 | PRMT3 (0.48) | PRMT3ALDH1A1NPC1POLBMAPT | |
| SCHEMBL1291431 | 0.69 | NPC1 (0.42) | PRMT3ALDH1A1NPC1POLBMAPT | |
| SCHEMBL506620 | 0.69 | NPC1 (0.51) | ALDH1A1NPC1RAB9AHSD17B10APP | |
| SCHEMBL14582771 | 0.69 | THRB (0.42) | ALDH1A1NPC1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976027-A1 | FACTOR XI ACTIVATION INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2022-04-06 | — | — | EP | disclosed |