Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472926 | 0.80 | ALDH1A1 (0.39) | CA1CA2ALDH1A1MAPTPARP1 | |
| SCHEMBL11252922 | 0.79 | ERN1 (0.44) | ERN1CA1CA2TRIM24TRIM33 | |
| SCHEMBL30549532 | 0.79 | IDO1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL207829 | 0.79 | IDO1 (0.47) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30549508 | 0.78 | IDO1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL1042068 | 0.78 | IDO1 (0.42) | ALDH1A1MAPTTTR | |
| SCHEMBL28117640 | 0.77 | TRPA1 (0.39) | CA1CA2ALDH1A1MAPTPARP1 | |
| Hydrochloric Acid SCHEMBL21412101 | 0.77 | MAOA (0.37) | CA1CA2ALDH1A1MAPTTHRB | |
| SCHEMBL5613032 | 0.77 | MEN1 (0.32) | PARP1 | |
| SCHEMBL11355260 | 0.75 | XDH (0.46) | TRIM24TRIM33ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062799-B | Methoxy-substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111943998-B | Methyl mercapto substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111909230-B | Chlorine-substituted arabinose triazole structure spiro isoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111961101-B | Spiroisoxazole-pyrrolizine derivative with arabinose triazole structure as well as preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111961100-B | Fluorine-substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-112028955-B | Trimethoxylated arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111961099-B | Methyl-substituted arabinose triazole structure spiro isoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| CN-111909230-B | Chlorine-substituted arabinose triazole structure spiro isoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-112062799-B | Methoxy-substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-111943998-B | Methyl mercapto substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-111961101-B | Spiroisoxazole-pyrrolizine derivative with arabinose triazole structure as well as preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-112028955-B | Trimethoxylated arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-111961100-B | Fluorine-substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-111961099-B | Methyl-substituted arabinose triazole structure spiro isoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | disclosed |