SCHEMBL164316

SCHEMBL164316

O=C(ON1C(=O)CCC1=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.56
MAPT P10636 3/20 0.56
MEN1 O00255 2/20 0.56
HTT P42858 2/20 0.56
KMT2A Q03164 2/20 0.56
HPGD P15428 2/20 0.56
CYP2C19 P33261 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
SMAD3 P84022 1/20 0.56
PRMT1 Q99873 1/20 0.56
ACE2 Q9BYF1 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
USP2 O75604 1/20 0.42
ALOX12 P18054 2/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29995636 1.00 FTO (0.56) FTOMAPTMEN1HTTKMT2A
SCHEMBL29501272 1.00 FTO (0.56) FTOMAPTMEN1HTTKMT2A
SCHEMBL30064563 1.00 FTO (0.56) FTOMAPTMEN1HTTKMT2A
SCHEMBL29579867 0.96 FTO (0.55) FTOMAPTMEN1HTTKMT2A
SCHEMBL334086 0.93 FTO (0.55) FTOMAPTMEN1HTTKMT2A
SCHEMBL31580193 0.93 FTO (0.55) FTOMAPTMEN1HTTKMT2A
SCHEMBL29383733 0.93 FTO (0.55) FTOMAPTMEN1HTTKMT2A
SCHEMBL27645069 0.88 FTO (0.52) FTOMAPTMEN1HTTKMT2A
SCHEMBL20339897 0.88 FTO (0.53) FTOMAPTMEN1HTTKMT2A
SCHEMBL29569825 0.87 ALDH1A1 (0.46) FTOMAPTMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002954-A1 Novel Compound, Use Thereof, and Method for Producing Same, and Compound-Containing Composition, Method for Producing 4-Trehalosamine, and Microorganism MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 2025-01-02 US claimed
CN-118922553-A Novel compound, use thereof, preparation method thereof, composition containing compound, preparation method of 4-trehalose amine and microorganism 公益财团法人微生物化学研究会 2024-11-08 CN claimed
US-12105092-B2 Molecularly imprinted particles GEORGE MASON UNIVERSITY (US) 2024-10-01 US claimed
EP-4400596-A1 NOVEL COMPOUND, USE THEREOF, METHOD FOR PRODUCING SAME, COMPOUND-CONTAINING COMPOSITION, METHOD FOR PRODUCING 4-TREHALOSAMINE, AND MICROORGANISM Microbial Chemistry Research Foundation (JP) 2024-07-17 EP claimed
WO-2023032788-A1 NOVEL COMPOUND, USE THEREOF, METHOD FOR PRODUCING SAME, COMPOUND-CONTAINING COMPOSITION, METHOD FOR PRODUCING 4-TREHALOSAMINE, AND MICROORGANISM 公益財団法人微生物化学研究会 2023-03-09 WO claimed
CN-114199653-A Microbial immunofluorescence staining solution for vagina 济南德亨医学科技有限公司 2022-03-18 CN claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-111620918-A 8-beta-D-glucopyranose-4', 7-dihydroxyisoflavone FAM derivative and synthetic method thereof 辽宁中医药大学 2020-09-04 CN claimed
CN-109553566-B Anti-counterfeiting material with adjustable imaging waveband and preparation method and application thereof 北京化工大学 2020-05-01 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
WO-2014209300-A1 ELECTROPHORETIC DISPLAYS HAVING CHARGED FLUORESCENT DENDRIMER PARTICLES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-31 WO claimed
CN-101735802-A Double-chromophore fluorescent probe and preparation method UNIV TIANJIN POLYTECHNIC 2010-06-16 CN claimed
US-12454531-B2 Substituted piperazine derivatives useful as T cell activators BRISTOL-MYERS SQUIBB COMPANY (US) 2025-10-28 US disclosed
CN-120192374-A Targeted SctV cyclic peptide for inhibiting T3SS activity and application thereof 山东大学 2025-06-24 CN disclosed
US-20250002954-A1 Novel Compound, Use Thereof, and Method for Producing Same, and Compound-Containing Composition, Method for Producing 4-Trehalosamine, and Microorganism MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 2025-01-02 US disclosed
CN-118922553-A Novel compound, use thereof, preparation method thereof, composition containing compound, preparation method of 4-trehalose amine and microorganism 公益财团法人微生物化学研究会 2024-11-08 CN disclosed
US-4912208-A Spiro(phthalan-1,9'-xanthene) ring ABBOTT LABORATORIES (US) 1990-03-27 US disclosed
EP-0108399-B1 SUBSTITUTED CARBOXYFLUORESCEINS ABBOTT LABORATORIES (US) 1987-09-23 EP disclosed
US-4476229-A QUANTITATIVE ANALYSIS OF LIGANDS IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 1984-10-09 US disclosed
EP-0108399-A2 Substituted carboxyfluoresceins ABBOTT LABORATORIES (US) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454531-B2 Substituted piperazine derivatives useful as T cell activators DGKZ, DGKA, DGKG FTO 4445/4885MAPT 4488/4885MEN1 3209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.