Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100965 | 0.84 | PPARG (0.55) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL10692667 | 0.84 | PPARG (0.55) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL4565010 | 0.82 | CTSG (0.50) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL2957410 | 0.82 | CTSG (0.50) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL10690483 | 0.82 | PPARG (0.51) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL10690468 | 0.82 | PPARG (0.51) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL28085748 | 0.81 | MAPK1 (0.49) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL10690475 | 0.81 | MMP9 (0.48) | GAAMAPTMAPK1NPSR1MMP9 | |
| Hydrochloric Acid SCHEMBL1499448 | 0.80 | MMP9 (0.47) | GAAMAPTMAPK1NPSR1MMP9 | |
| SCHEMBL6331296 | 0.80 | MMP9 (0.61) | GAAMAPTMMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708740-B1 | PROTEASE INHIBITORS FOR THE TREATMENT OF DIGESTIVE PATHOLOGIES | RYTEK (FR) | 2010-09-29 | — | — | EP | claimed |
| EP-1708740-B1 | PROTEASE INHIBITORS FOR THE TREATMENT OF DIGESTIVE PATHOLOGIES | RYTEK (FR) | 2010-09-29 | — | — | EP | disclosed |