Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265358 | 1.00 | NPC1 (0.42) | NPC1RAB9AHSP90AA1KDM4EPABPC1 | |
| SCHEMBL26482558 | 0.86 | FGFR1 (0.36) | NPC1RAB9AACSS2FGFR1SMN1; SMN2 | |
| SCHEMBL29574433 | 0.85 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26494819 | 0.85 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29040744 | 0.85 | HCAR3 (0.40) | NPC1RAB9AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL24265947 | 0.74 | IDH1 (0.40) | NPC1RAB9AHSP90AA1KDM4EHSD17B10 | |
| SCHEMBL29573838 | 0.74 | IDH1 (0.40) | NPC1RAB9AHSP90AA1KDM4EHSD17B10 | |
| SCHEMBL24265362 | 0.73 | TP53 (0.54) | KDM4EMAPTLMNA | |
| SCHEMBL30548145 | 0.73 | TP53 (0.54) | KDM4EMAPTLMNA | |
| SCHEMBL25434066 | 0.72 | ACSS2 (0.43) | NPC1RAB9AHSP90AA1KDM4EPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |