Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717358 | 1.00 | RAB9A (0.45) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL22732283 | 0.78 | MEN1 (0.44) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL28999775 | 0.78 | RAB9A (0.45) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL30427603 | 0.78 | RAB9A (0.45) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL22717660 | 0.77 | MEN1 (0.38) | POLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL22717580 | 0.76 | SIRT6 (0.33) | DGAT1 | |
| SCHEMBL2134732 | 0.76 | ALDH1A1 (0.57) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL10174988 | 0.73 | RAB9A (0.56) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL7045810 | 0.73 | ALDH1A1 (0.43) | RAB9AALDH1A1NPC1POLBDGAT1 | |
| SCHEMBL22731834 | 0.73 | DGAT1 (0.44) | RAB9AALDH1A1NPC1POLBDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976608-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |