SCHEMBL29577010

C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CALCRL	Q16602	6/20	0.47

▸	EPHA2	P29317	2/20	0.43

▸	KEAP1	Q14145	1/20	0.43

▸	EP300	Q09472	1/20	0.41

▸	HIF1A	Q16665	1/20	0.41

▸	RAMP3	O60896	5/20	0.40

▸	CALCR	P30988	5/20	0.40

▸	MAPK8	P45983	1/20	0.40

▸	MAPK9	P45984	1/20	0.40

▸	MAPK10	P53779	1/20	0.40

▸	ACE	P12821	3/20	0.40

▸	REN	P00797	2/20	0.40

▸	RAMP1	O60894	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30167875	0.90	CAPN1 (0.38)	CALCRLRAMP3CALCRMAPK8MAPK9
SCHEMBL31214780	0.88	EPHA2 (0.52)	CALCRLEPHA2KEAP1ACEREN
SCHEMBL31039948	0.88	CXCR4 (0.47)	EPHA2ACE
SCHEMBL31344445	0.86	KEAP1 (0.51)	KEAP1RAMP3CALCRMAPK8MAPK9
SCHEMBL30471842	0.85	ACE (0.41)	ACEREN
SCHEMBL9551335	0.85	EPHA2 (0.46)	CALCRLEPHA2ACE
SCHEMBL30844081	0.85	MAPK8 (0.45)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL29802056	0.85	OPRK1 (0.46)	ACE
SCHEMBL30957282	0.84	EPHA2 (0.49)	CALCRLEPHA2RAMP3CALCRMAPK8
SCHEMBL31307294	0.84	NPY2R (0.51)	EP300HIF1ARAMP3CALCRMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11312974-B2	Gene for increasing plant biomass and use therefor	KANEKA CORPORATION (JP)	2022-04-26	—	—	US	disclosed