SCHEMBL31344445

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O

nearest known ligand 0.51

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.51

▸	RAMP3	O60896	14/20	0.49

▸	CALCR	P30988	14/20	0.49

▸	MAPK8	P45983	1/20	0.46

▸	MAPK9	P45984	1/20	0.46

▸	MAPK10	P53779	1/20	0.46

▸	PLK1	P53350	1/20	0.45

▸	NPY4R	P50391	2/20	0.44

▸	NPY1R	P25929	1/20	0.44

▸	NPY2R	P49146	1/20	0.44

▸	NPY5R	Q15761	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29776766	0.89	MAPK8 (0.58)	KEAP1RAMP3CALCRMAPK8MAPK9
SCHEMBL30443975	0.88	ACE (0.45)	KEAP1RAMP3CALCRPLK1NPY4R
SCHEMBL31481586	0.87	OPRK1 (0.47)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL30974082	0.87	RAMP3 (0.55)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL29651846	0.87	KEAP1 (0.53)	KEAP1RAMP3CALCRMAPK8MAPK9
SCHEMBL29651851	0.87	KEAP1 (0.53)	KEAP1RAMP3CALCRMAPK8MAPK9
SCHEMBL30817470	0.86	KEAP1 (0.43)	KEAP1RAMP3CALCRNPY4RNPY1R
SCHEMBL30974076	0.86	ACE (0.47)	RAMP3CALCR
SCHEMBL31419820	0.86	NTSR2 (0.44)	PLK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL29466786	0.86	MAPK8 (0.47)	RAMP3CALCRMAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025027181-A1	AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS	BioNTech SE (DE)	2025-02-06	—	—	WO	disclosed