SCHEMBL29580903

SCHEMBL29580903

CCc1cccc(OC(=O)Oc2cccc(CC)c2CC)c1CC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
NCEH1 Q6PIU2 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
PPARA Q07869 2/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ELANE P08246 1/20 0.38
PPARG P37231 1/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
NLRP3 Q96P20 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988680 1.00 GABRA1 (0.43) GABRA1GABRB2NCEH1L3MBTL1PPARA
SCHEMBL1841644 0.95 L3MBTL1 (0.42) GABRA1GABRB2NCEH1L3MBTL1MAPT
SCHEMBL1840022 0.93 NCEH1 (0.39) GABRA1GABRB2NCEH1L3MBTL1PPARA
SCHEMBL1836456 0.91 KDM4E (0.49) GABRA1GABRB2NCEH1L3MBTL1MAPT
SCHEMBL1836772 0.90 TDP1 (0.41) NCEH1L3MBTL1NPSR1PPARGNLRP3
SCHEMBL28814511 0.90 MAPT (0.39) GABRA1GABRB2NCEH1L3MBTL1PPARA
SCHEMBL1838036 0.90 TYMS (0.44) GABRA1GABRB2NCEH1L3MBTL1MAPT
SCHEMBL1838821 0.89 LTB4R (0.44) GABRA1GABRB2NCEH1PPARAELANE
SCHEMBL1838116 0.89 POLB (0.46) L3MBTL1MAPTNLRP3
SCHEMBL1837676 0.89 THRA (0.45) NCEH1PPARANPSR1PPARGMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed