Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 8/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423770 | 0.85 | SCD (0.31) | KDM5ACHRM4 | |
| SCHEMBL24422937 | 0.84 | TDP1 (0.32) | HCRTR2HCRTR1SMN1; SMN2CHRM4 | |
| SCHEMBL24423714 | 0.79 | MGLL (0.33) | KDM5ANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL29585305 | 0.79 | MGLL (0.33) | KDM5ANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL24423448 | 0.79 | MGLL (0.33) | KDM5ANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL24423040 | 0.79 | FFAR2 (0.35) | KDM5ANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL30630747 | 0.78 | CHRM4 (0.35) | NPC1ALDH1A1HPGDRAB9ACHRM4 | |
| SCHEMBL24424032 | 0.78 | CHRM4 (0.35) | NPC1ALDH1A1HPGDRAB9ACHRM4 | |
| SCHEMBL24424425 | 0.78 | NPC1 (0.42) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24423866 | 0.78 | GAA (0.40) | KDM5ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |