Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587478 | 0.79 | ESR2 (0.46) | ACLYESR2MAPTALOX15ALOX12 | |
| SCHEMBL5459938 | 0.79 | CNR2 (0.53) | L3MBTL1ACLYAKR1C2AKR1C1CNR2 | |
| SCHEMBL29586685 | 0.79 | HDAC4 (0.50) | ACLYGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27505789 | 0.77 | ESR2 (0.50) | AKR1C2AKR1C1ESR2THRB | |
| SCHEMBL17364433 | 0.77 | ESR2 (0.66) | L3MBTL1AKR1C2AKR1C1CNR1ESR2 | |
| SCHEMBL26348798 | 0.75 | CNR2 (0.50) | L3MBTL1ACLYAKR1C2AKR1C1CNR2 | |
| SCHEMBL5536644 | 0.74 | L3MBTL1 (0.49) | L3MBTL1AKR1C2AKR1C1CNR2CNR1 | |
| SCHEMBL5462846 | 0.73 | ACLY (0.51) | ACLYMAPT | |
| SCHEMBL9742743 | 0.73 | ALOX15 (0.52) | L3MBTL1ACLYAKR1C2AKR1C1CNR2 | |
| SCHEMBL23309016 | 0.72 | ACHE (0.52) | L3MBTL1ACLYAKR1C2AKR1C1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478337-A | Axial chiral sulfur-containing diaryl derivative and synthesis method thereof | 安徽泽升科技有限公司上海分公司 | 2022-05-13 | — | — | CN | disclosed |