SCHEMBL29586994

SCHEMBL29586994

O=C1CCC(Sc2cnccn2)CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23295261 0.80 PDGFRB (0.40) LMNA
SCHEMBL21047774 0.76 CRBN (0.54) DDB1CRBN
SCHEMBL28283901 0.72 NPC1 (0.44) LMNADDB1CRBN
SCHEMBL21047745 0.71 CRBN (0.49) LMNADDB1CRBN
SCHEMBL627925 0.69 ESR2 (0.36)
SCHEMBL28282297 0.68 HPGD (0.45) LMNA
SCHEMBL28282312 0.68 DDB1 (0.33) DDB1CRBN
SCHEMBL29587137 0.66 ALDH1A1 (0.40) LMNADDB1CRBN
SCHEMBL21047684 0.66 MEN1 (0.31)
SCHEMBL21047766 0.66 FDPS (0.34) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563016-B Method for producing perfluoroalkyl compound using monohydroperfluoroalkane as starting material 关东电化工业株式会社 2022-05-13 CN disclosed