Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735948 | 1.00 | MEN1 (0.42) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL3561759 | 0.87 | SIRT2 (0.40) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL14870330 | 0.83 | CYP2A6 (0.44) | MEN1KMT2AKDM4EPOLBRXFP1 | |
| SCHEMBL23252382 | 0.77 | ESR2 (0.35) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL3568497 | 0.76 | MAPT (0.52) | MEN1KMT2AGAAMAOBLMNA | |
| SCHEMBL154708 | 0.74 | LMNA (0.65) | MEN1KMT2AMAOBLMNAMAPT | |
| SCHEMBL29459415 | 0.74 | LMNA (0.65) | MEN1KMT2AMAOBLMNAMAPT | |
| SCHEMBL18703963 | 0.74 | MEN1 (0.36) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL18032999 | 0.74 | AHR (0.36) | LMNAMAPTHTTBLMAHR | |
| SCHEMBL8231432 | 0.74 | GPR84 (0.52) | KDM4EGAALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108138052-B | Chiral compounds | 默克专利股份有限公司 | 2022-04-12 | — | — | CN | disclosed |