SCHEMBL2958797

SCHEMBL2958797

Cc1ccc[c]c1C(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1069174 0.79 ACHE (0.33) TSHRACHE
SCHEMBL6997827 0.77 DAO (0.35) TSHRACHE
SCHEMBL159454 0.76 GABRA1 (0.41) TSHRCYP1A2ALDH1A1
SCHEMBL3821405 0.76
SCHEMBL7457176 0.74 LMNA (0.33) TSHRCYP1A2ALDH1A1
SCHEMBL2139424 0.74 ACHE (0.32) ACHE
SCHEMBL555031 0.74 GABRA1 (0.43) TSHRCYP1A2ALDH1A1
SCHEMBL15414904 0.74 CYP3A4 (0.39) TSHR
SCHEMBL19405603 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27960211 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2838359-A1 SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES California Institute of Technology (US) 2015-02-25 EP claimed
WO-2013134192-A1 SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-09-12 WO claimed
US-20130231499-A1 SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES CALIFORNIA INSTITUTE OF TECHNOLOGY 2013-09-05 US claimed
CN-1166176-A Thermal metathesis polymerisation process and a polymerisable compsn. CIBA GEIGY AG (CH) 1997-11-26 CN claimed
CN-114401946-A MAGL inhibitor and preparation method and application thereof 鲁南制药集团股份有限公司 2022-04-26 CN disclosed
EP-3024865-A1 MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR PROPERTIES Momentive Performance Materials Inc. (US) 2016-06-01 EP disclosed
US-9234985-B2 Birefringent polymer brush structures formed by surface initiated ring-opening metathesis polymerization CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-01-12 US disclosed
US-9147844-B2 Solvent-free enyne metathesis polymerization CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2015-09-29 US disclosed
US-8987531-B2 Syntheses of Z-olefin-containing lepidopteran insect pheromones CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2015-03-24 US disclosed
EP-2838359-A1 SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES California Institute of Technology (US) 2015-02-25 EP disclosed
WO-2015013407-A1 MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR PROPERTIES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-01-29 WO disclosed
US-20140049823-A1 BIREFRINGENT POLYMER BRUSH STRUCTURES FORMED BY SURFACE INITIATED RING-OPENING METATHESIS POLYMERIZATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-02-20 US disclosed
US-4097675-A 8β, 12α, 15β-PGF2α Compounds THE UPJOHN COMPANY (US) 1978-06-27 US disclosed
US-4096342-A 8β,12α,15β-PGE2 compounds THE UPJOHN COMPANY (US) 1978-06-20 US disclosed
US-4095036-A 8β,12α,15β-PGF2 β Compounds THE UPJOHN COMPANY (US) 1978-06-13 US disclosed
US-4084063-A PROSTAGLANDINS; ANTIULCER AGENTS, ANTICOAGULANTS, OXYTOCICS, DECONGESTANTS THE UPJOHN COMPANY (US) 1978-04-11 US disclosed
US-3987085-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3969396-A 8β, 11β, 12α-PGE2 compounds THE UPJOHN COMPANY (US) 1976-07-13 US disclosed
US-3965118-A Lactone intermediates THE UPJOHN COMPANY (US) 1976-06-22 US disclosed
US-3960873-A 1-Phenylthiopropyl-4-hydroxy-4-phenyl piperidines SUMITOMO CHEMICAL CO., LTD. (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231499-A1 SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES ZYX, OSBP, ZDHHC7 TSHR 3480/4885ACHE 113/4885CYP1A2 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.