SCHEMBL29588151

SCHEMBL29588151

Cc1ccccc1Sc1ccc([Si](C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.44
HAO1 Q9UJM8 1/20 0.42
ALDH1A1 P00352 2/20 0.40
FFAR1 O14842 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HTR1A P08908 3/20 0.36
HTR3A P46098 3/20 0.36
HTR2C P28335 1/20 0.35
HTR6 P50406 1/20 0.35
SLC6A2 P23975 3/20 0.34
SLC6A4 P31645 3/20 0.34
SLC6A3 Q01959 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20955821 1.00 AR (0.44) ARHAO1ALDH1A1FFAR1L3MBTL1
SCHEMBL20955833 0.83 AR (0.43) ARHAO1ALDH1A1FFAR1L3MBTL1
SCHEMBL30670355 0.79 HTR1A (0.49) ARHAO1ALDH1A1FFAR1L3MBTL1
SCHEMBL11602202 0.79 HTR1A (0.49) ARHAO1ALDH1A1FFAR1L3MBTL1
SCHEMBL2876479 0.79 L3MBTL1 (0.50) ARHAO1FFAR1L3MBTL1HTR1A
SCHEMBL29580858 0.79 L3MBTL1 (0.50) ARHAO1FFAR1L3MBTL1HTR1A
SCHEMBL20955820 0.77 ALDH1A1 (0.47) ALDH1A1L3MBTL1SLC6A4SMN1; SMN2
SCHEMBL18620896 0.76 CYP3A4 (0.52) ARHAO1ALDH1A1FFAR1L3MBTL1
SCHEMBL153572 0.76 NR1H2 (0.52) ARHAO1FFAR1L3MBTL1HTR1A
SCHEMBL2154888 0.76 AR (0.46) ARHAO1ALDH1A1FFAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480205-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN APRO LTD (JP) 2022-04-13 EP disclosed