SCHEMBL20955820

SCHEMBL20955820

C[Si](C)(C)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
MAOA P21397 3/20 0.45
MAOB P27338 3/20 0.45
SLC6A4 P31645 1/20 0.42
MAPT P10636 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MGLL Q99685 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CHRNA7 P36544 1/20 0.36
PTGIR P43119 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.35
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3891151 0.79 MAOA (0.62) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL23277364 0.79 MAOA (0.62) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL3891569 0.79 MAOA (0.62) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL795030 0.79 MAOA (0.62) ALDH1A1HPGDMAOAMAOBSLC6A4
Diphenylsulfane SCHEMBL29268628 0.78 ESR1 (0.54) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL14216508 0.78 MAOA (0.46) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL20955821 0.77 AR (0.44) ALDH1A1SLC6A4SMN1; SMN2L3MBTL1
SCHEMBL10406863 0.76 ALDH1A1 (0.47) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL92396 0.76 ESR1 (0.48) ALDH1A1HPGDMAPTSMN1; SMN2ESR1
Diphenylsulfane SCHEMBL28332331 0.76 HPGD (0.60) ALDH1A1HPGDMAOAMAOBSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480205-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN APRO LTD (JP) 2022-04-13 EP disclosed
CN-108884110-B Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof 三亚普罗股份有限公司 2021-09-14 CN disclosed
US-10683266-B2 Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof SAN APRO LTD. (JP) 2020-06-16 US disclosed
US-20190300476-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN-APRO LTD. (JP) 2019-10-03 US disclosed
EP-3480205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF San-Apro Ltd. (JP) 2019-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190300476-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF ASIC1, TST, SPIN2B ALDH1A1 821/4885HPGD 1111/4885MAOA 3643/4885
US-10683266-B2 Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof ASIC1, TST, SPIN2B ALDH1A1 821/4885HPGD 1111/4885MAOA 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.