SCHEMBL29590258

SCHEMBL29590258

CC(C)[C@H](N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 1/20 0.41
▸ GRB2 P62993 1/20 0.40
▸ APLNR P35414 1/20 0.39
▸ DPP4 P27487 1/20 0.38
▸ PREP P48147 1/20 0.38
▸ FAP Q12884 1/20 0.38
▸ ACE P12821 11/20 0.37
▸ REN P00797 2/20 0.37
▸ ACE2 Q9BYF1 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589474 0.89 ACE (0.46) APLNRFAPACE
SCHEMBL30671934 0.88 ACE (0.45) GRB2ACERENACE2
SCHEMBL30575171 0.85 PREP (0.42) DPP4PREPFAPACEREN
SCHEMBL30385933 0.84 GRB2 (0.48) NAA50GRB2APLNR
SCHEMBL29589425 0.83 ACE (0.43) DPP4PREPFAPACEREN
SCHEMBL30052339 0.82 PREP (0.49) DPP4PREPFAPACEREN
SCHEMBL31593272 0.82 PLK1 (0.38) NAA50APLNR
SCHEMBL30379247 0.82 PLK1 (0.41) NAA50APLNRACEACE2
SCHEMBL29591172 0.82 PREP (0.44) DPP4PREPFAPACEREN
SCHEMBL31437158 0.81 ACE (0.43) GRB2ACERENACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP claimed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US claimed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP claimed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 — — EP claimed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO claimed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP disclosed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US disclosed
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2024-04-16 — — US disclosed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP disclosed
EP-4257156-A2 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2023-10-11 — — EP disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 — — EP disclosed
EP-4103236-B1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY INC (US) 2023-08-16 — — EP disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed
EP-4103236-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2022-12-21 — — EP disclosed
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2022-12-01 — — US disclosed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO disclosed
WO-2022093793-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR NAA50 2490/4885GRB2 265/4885APLNR 165/4885
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES TLR7, TLR8, TLR9 NAA50 2703/4885GRB2 137/4885APLNR 491/4885
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR NAA50 2490/4885GRB2 265/4885APLNR 165/4885
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP NAA50 2058/4885GRB2 1083/4885APLNR 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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