Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591015 | 0.94 | BCL2 (0.53) | BCL2 | |
| SCHEMBL29590466 | 0.83 | HSP90AA1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16416972 | 0.83 | HSP90AA1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29590775 | 0.83 | HSP90AA1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29589794 | 0.82 | BCL2 (0.57) | BCL2 | |
| SCHEMBL29591192 | 0.82 | BCL2 (0.51) | BCL2ALDH1A1 | |
| SCHEMBL29590211 | 0.81 | RAB9A (0.62) | BCL2ALDH1A1MEN1KMT2A | |
| SCHEMBL29590139 | 0.80 | NR1H2 (0.56) | BCL2 | |
| SCHEMBL29589831 | 0.79 | OPRM1 (0.43) | BCL2 | |
| SCHEMBL29590949 | 0.79 | NAMPT (0.42) | BCL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |