SCHEMBL2959103

SCHEMBL2959103

FC1=Cc2ccc(Br)cc2C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.36
AHR P35869 1/20 0.36
PNMT P11086 5/20 0.36
ADRA2A P08913 2/20 0.36
METAP1 P53582 1/20 0.35
TDP2 O95551 1/20 0.34
ASIC3 Q9UHC3 1/20 0.33
TRPA1 O75762 1/20 0.32
KDM1A O60341 2/20 0.32
KDM1B Q8NB78 1/20 0.32
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP11 Q9NR21 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
ABHD6 Q9BV23 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2963640 0.83 TRPA1 (0.42) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2975971 0.79 PNMT (0.37) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2973732 0.75 ALDH1A1 (0.37) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2970165 0.75 CYP11B1 (0.33) PNMTADRA2AMETAP1TDP2ASIC3
SCHEMBL2972221 0.71 PNMT (0.37) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2971259 0.71 METAP1 (0.36) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2967305 0.71 METAP1 (0.33) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2962956 0.71 TRPA1 (0.33) CMA1AHRPNMTADRA2AMETAP1
SCHEMBL2964136 0.69 CYP11B1 (0.42) PNMTASIC3TRPA1SLC6A2HTR2A
SCHEMBL12237688 0.69 SRD5A1 (0.44) CMA1AHRPNMTMETAP1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 CMA1 4380/4885AHR 991/4885PNMT 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.