Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971729 | 0.85 | TRPA1 (0.39) | PNMTADRA2AKDM1AMETAP1TDP2 | |
| SCHEMBL2959103 | 0.79 | CMA1 (0.36) | PNMTADRA2AKDM1AMETAP1TDP2 | |
| SCHEMBL2973732 | 0.71 | ALDH1A1 (0.37) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL2971259 | 0.67 | METAP1 (0.36) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL2970165 | 0.67 | CYP11B1 (0.33) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL2962956 | 0.67 | TRPA1 (0.33) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL2967305 | 0.67 | METAP1 (0.33) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL2972221 | 0.67 | PNMT (0.37) | PNMTADRA2AMETAP1TDP2ASIC3 | |
| SCHEMBL16532174 | 0.66 | ADRA2A (0.31) | PNMTADRA2AABHD6 | |
| SCHEMBL12237688 | 0.66 | SRD5A1 (0.44) | PNMTMETAP1TDP2ASIC3CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | PNMT 2021/4885ADRA2A 2587/4885KDM1A 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.