SCHEMBL29598775

SCHEMBL29598775

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 2/20 0.62
▸ GRPR P30550 2/20 0.62
▸ CCKBR P32239 2/20 0.59
▸ GLP1R P43220 2/20 0.59
▸ PRLHR P49683 5/20 0.58
▸ KISS1R Q969F8 3/20 0.58
▸ NPY1R P25929 1/20 0.57
▸ NPY2R P49146 1/20 0.57
▸ NPY4R P50391 1/20 0.57
▸ NPY5R Q15761 1/20 0.57
▸ OPRD1 P41143 1/20 0.57
▸ IL23R Q5VWK5 1/20 0.57
▸ AGTR1 P30556 1/20 0.57
▸ AGTR2 P50052 1/20 0.57
▸ NPFFR2 Q9Y5X5 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29599104 0.87 NPY1R (0.65) GLP1RPRLHRKISS1RNPY1RNPY2R
SCHEMBL31441008 0.84 CXCR4 (0.63) CCKBRGLP1RPRLHRNPY1RNPY2R
SCHEMBL29455091 0.83 KISS1R (0.59) NMBRGRPRKISS1RNPY1RNPY2R
SCHEMBL31105379 0.83 NPY1R (0.64) CCKBRGLP1RNPY1RNPY2RNPY4R
SCHEMBL38664590 0.83 NPY1R (0.57) CCKBRGLP1RPRLHRKISS1RNPY1R
Dynorphin A (1-17) SCHEMBL29599476 0.82 OPRD1 (0.70) NMBRGRPROPRD1
Dynorphin A (1-17) SCHEMBL29358748 0.82 OPRD1 (0.70) NMBRGRPROPRD1
SCHEMBL31182444 0.82 NPY2R (0.70) CCKBRGLP1RNPY1RNPY2RNPY4R
SCHEMBL29811065 0.82 NPY2R (0.71) CCKBRGLP1RNPY1RNPY2RNPY4R
SCHEMBL38654334 0.82 NPY2R (0.70) GLP1RPRLHRNPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 — — WO claimed
US-12590131-B2 Antimicrobial peptides with alpha-core helices LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2026-03-31 — — US disclosed
US-12583900-B2 Peptide conjugates and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2026-03-24 — — US disclosed
EP-4626459-A1 PALMITOYLATED ANALOGUE OF PROLACTIN-RELEASING PEPTIDE FOR INTRANASAL ADMINISTRATION Ustav organicke chemie a biochemie Akademie ved CR, v.v.i. (CZ) 2025-10-08 — — EP disclosed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 — — WO disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 — — US disclosed
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2024-08-22 — — US disclosed
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation TUFTS MEDICAL CENTER (US) 2024-08-13 — — US disclosed
WO-2024114846-A1 PALMITOYLATED ANALOGUE OF PROLACTIN-RELEASING PEPTIDE FOR INTRANASAL ADMINISTRATION USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CR, V. V. I. (CZ) 2024-06-06 — — WO disclosed
US-11987607-B2 Antimicrobial peptides with alpha-core helices The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (US) 2024-05-21 — — US disclosed
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER 2023-07-20 — — US disclosed
US-20230071371-A1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2023-03-09 — — US disclosed
CN-115232201-A PrRP31 modified by polyethylene glycol and preparation and application thereof 西北工业大学 2022-10-25 — — CN disclosed
EP-4069274-A1 PEPTIDE CONJUGATES AND METHODS OF USE The Scripps Research Institute (US) 2022-10-12 — — EP disclosed
CN-115052615-A Peptide conjugates and methods of use 斯克利普斯研究所 2022-09-13 — — CN disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG NMBR 1416/4885GRPR 936/4885CCKBR 2086/4885
US-12590131-B2 Antimicrobial peptides with alpha-core helices VIP, HAMP, HM13 NMBR 3567/4885GRPR 669/4885CCKBR 3032/4885
US-12583900-B2 Peptide conjugates and methods of use GIPR, GLP1R, GCG NMBR 1671/4885GRPR 4/4885CCKBR 16/4885
US-11987607-B2 Antimicrobial peptides with alpha-core helices VIP, NGLY1, SPPL2B NMBR 2546/4885GRPR 588/4885CCKBR 2734/4885
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B NMBR 2546/4885GRPR 588/4885CCKBR 2734/4885
US-20230071371-A1 PEPTIDE CONJUGATES AND METHODS OF USE GIPR, GLP1R, GRPR NMBR 756/4885GRPR 3/4885CCKBR 25/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG NMBR 1416/4885GRPR 936/4885CCKBR 2086/4885
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B NMBR 2546/4885GRPR 588/4885CCKBR 2734/4885
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation LIPG, CD40, LDLR NMBR 1403/4885GRPR 775/4885CCKBR 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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