Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CCND1 | P24385 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928925 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL15785123 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL15908319 | 0.79 | HTR2A (0.46) | ALDH1A1MAPTLMNAOPRM1OPRL1 | |
| SCHEMBL1581750 | 0.79 | MAPT (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29366795 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AALOX15KDM4E | |
| SCHEMBL15704262 | 0.78 | HRH3 (0.49) | ALDH1A1MEN1KMT2AKDM4EOPRM1 | |
| SCHEMBL15908317 | 0.77 | HTR2A (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1961099 | 0.77 | SIGMAR1 (0.61) | OPRM1OPRL1OPRK1SIGMAR1HRH3 | |
| SCHEMBL1868503 | 0.76 | OPRL1 (0.60) | OPRM1OPRL1OPRK1SIGMAR1CHRM3 | |
| Hydrochloric Acid SCHEMBL17940592 | 0.76 | KMT2A (0.49) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912488-B | Method for synthesizing 3-alkyl indoline by alkylation of non-activated olefin under catalysis of copper | 昆明学院 | 2022-05-10 | — | — | CN | disclosed |