Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934890 | 0.83 | HTR2C (0.58) | OPRL1OPRM1OPRK1OPRD1HTR2C | |
| SCHEMBL1961099 | 0.80 | SIGMAR1 (0.61) | OPRL1OPRM1OPRK1SIGMAR1DRD2 | |
| SCHEMBL14349454 | 0.80 | OPRM1 (0.53) | OPRL1OPRM1OPRK1CHRM3OPRD1 | |
| SCHEMBL3878013 | 0.79 | OPRM1 (0.80) | OPRL1OPRM1OPRK1 | |
| SCHEMBL14282272 | 0.78 | OPRM1 (0.52) | OPRL1OPRM1OPRK1CHRM3OPRD1 | |
| SCHEMBL3723794 | 0.78 | OPRM1 (0.65) | OPRL1OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL5871358 | 0.77 | OPRM1 (0.51) | OPRL1OPRM1OPRK1OPRD1HTR2C | |
| SCHEMBL29600183 | 0.76 | ALDH1A1 (0.58) | OPRL1OPRM1OPRK1SIGMAR1CHRM3 | |
| SCHEMBL21307179 | 0.76 | HTR2C (0.60) | OPRL1OPRM1OPRK1SIGMAR1CHRM3 | |
| SCHEMBL21307175 | 0.76 | HTR2C (0.60) | OPRL1OPRM1OPRK1SIGMAR1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939670-B2 | Nociceptin analogs | PURDUE PHARMA L.P. (US) | 2011-05-10 | — | — | US | disclosed |