Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.38 |
| ▸ | MAOB | P27338 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24362288 | 1.00 | MAOA (0.38) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL1027802 | 0.92 | MAOB (0.37) | MAOBDRD2PTGS2DRD3 | |
| SCHEMBL12533716 | 0.86 | STS (0.36) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29600467 | 0.85 | MAOA (0.38) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL24362492 | 0.85 | MAOA (0.38) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL7501392 | 0.82 | MEN1 (0.39) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL24362286 | 0.78 | MAOA (0.36) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL1471642 | 0.77 | MAOB (0.55) | MAOAMAOBHSD17B1PRKCI | |
| SCHEMBL4809246 | 0.77 | MEN1 (0.41) | MAOAMEN1KMT2APTGS2 | |
| SCHEMBL2303778 | 0.77 | MEN1 (0.41) | MAOAMEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228758-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022084280-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |