Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88806 | 1.00 | CLK1 (0.40) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL29600021 | 0.83 | CLK1 (0.37) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL12460 | 0.83 | CLK1 (0.37) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| Isoquinoline SCHEMBL7076555 | 0.81 | EGFR (0.39) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL24987044 | 0.76 | MAP4K4 (0.48) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL6120009 | 0.75 | LOXL2 (0.31) | — | |
| Isoquinoline SCHEMBL6529066 | 0.74 | ALDH1A1 (0.55) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL1284991 | 0.74 | PDE3B (0.35) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL29599750 | 0.74 | PDE3B (0.35) | CLK1CSNK1DCSNK1EDYRK1AKDM4E | |
| SCHEMBL18099782 | 0.74 | IMPDH2 (0.43) | CLK1CSNK1DDYRK1AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4508052-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-119013278-A | Novel seven-membered ring fused compounds | 株式会社棱镜生物实验室 | 2024-11-22 | — | — | CN | disclosed |
| CN-110740996-B | Covalent small molecule DCN1 inhibitors and methods of treatment using the same | 密执安大学评议会 | 2024-01-09 | — | — | CN | disclosed |
| EP-4281456-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023200017-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-10-19 | — | — | WO | disclosed |
| EP-4225760-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023140369-A1 | PHOSPHORIC ACID DERIVATIVES | Prism BioLab Co., Ltd. (JP) | 2023-07-27 | — | — | WO | disclosed |
| CN-116348119-A | Novel bicyclic compounds | 株式会社棱镜生物实验室 | 2023-06-27 | — | — | CN | disclosed |
| CN-116018345-A | Novel heterocyclic compounds | 株式会社棱镜生物实验室 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022158610-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-07-28 | — | — | WO | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |