Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183167 | 1.00 | YTHDC1 (0.47) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL30496448 | 0.91 | CYP11B1 (0.50) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL21883488 | 0.91 | CYP11B1 (0.50) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL3425599 | 0.83 | ADORA2A (0.39) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL30496453 | 0.83 | ADORA2A (0.39) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL6900306 | 0.81 | MET (0.47) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL30020920 | 0.81 | MET (0.47) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL15921469 | 0.81 | P2RX7 (0.40) | ALDH1A1ADORA2A | |
| SCHEMBL5467085 | 0.81 | PDE4A (0.53) | YTHDC1SMN1; SMN2ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL17144368 | 0.80 | KMT2A (0.47) | SMN1; SMN2ALDH1A1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |