Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601705 | 0.79 | HTT (0.47) | P2RX7HTTSMN1; SMN2CA12CA7 | |
| SCHEMBL29601252 | 0.71 | P2RX7 (0.56) | P2RX7LMNATP53ALDH1A1 | |
| SCHEMBL12537200 | 0.70 | TLR9 (0.48) | P2RX7SMN1; SMN2LMNATP53ALDH1A1 | |
| SCHEMBL29601518 | 0.69 | P2RX7 (0.53) | P2RX7LMNATP53ALDH1A1 | |
| SCHEMBL11961123 | 0.67 | LMNA (0.48) | LMNATP53ALDH1A1ADORA3 | |
| SCHEMBL19204899 | 0.67 | P2RX7 (0.61) | P2RX7HTTL3MBTL1LMNAALDH1A1 | |
| SCHEMBL29601383 | 0.67 | P2RX7 (0.61) | P2RX7ALDH1A1PKM | |
| SCHEMBL25080403 | 0.66 | MTOR (0.48) | — | |
| SCHEMBL12537284 | 0.65 | USP2 (0.45) | P2RX7SMN1; SMN2L3MBTL1TSHRLMNA | |
| SCHEMBL29601575 | 0.65 | P2RX7 (0.77) | P2RX7L3MBTL1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |