Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802463 | 0.88 | P2RX7 (0.47) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL19746470 | 0.87 | P2RX7 (0.46) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL29601383 | 0.86 | P2RX7 (0.61) | P2RX7ALDH3A1NOD1ALDH1A1HDAC3 | |
| SCHEMBL29601246 | 0.86 | P2RX7 (0.57) | P2RX7NOD1HTTALDH1A1LMNA | |
| SCHEMBL19745997 | 0.82 | L3MBTL1 (0.48) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL27902479 | 0.78 | HTT (0.53) | P2RX7ALDH3A1L3MBTL1NOD1POLB | |
| SCHEMBL1015615 | 0.77 | ALDH1A1 (0.43) | ALDH3A1L3MBTL1NOD1POLBHTT | |
| SCHEMBL1015374 | 0.77 | L3MBTL1 (0.52) | ALDH3A1L3MBTL1NOD1POLBHTT | |
| SCHEMBL29601252 | 0.74 | P2RX7 (0.56) | P2RX7YTHDC1ALDH1A1LMNAHDAC3 | |
| SCHEMBL2203328 | 0.74 | LMNA (0.44) | ALDH3A1L3MBTL1NOD1HTTYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133664-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT， AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| CN-102850355-B | 9-sulfonyl-9H-purine derivatives, and preparation method and use thereof | UNIV SICHUAN | 2015-02-11 | — | — | CN | disclosed |